Process Development Associate (Cell Culture/Protein Purification)

Description: Top 3 Must Have Skill Sets: • Degree in Chemical Engineering, Biochemistry, Biotechnology, Bioengineering, Biomedical engineering, or Bioprocessing field or relevant experience in the pharmaceutical or related industry preferred. • 1+ years of relevant hands-on industry lab experience in cell culture or protein purification. (outside of education) • Attention to details and critical thinking ability. • Basic understanding of protein chromatography and filtration processes and hands-on industry experience with purification operations. • • 100% on-site in Thousand Oaks, CA • • • Must have lab experience at least one year working on similar projects • Ideal candidates will: work on culturing mammalian cells, maintaining bioreactors, sampling bioreactors. Must have lab experience at least one year working on similar projects. Manager wants to hire candidate with either masters and the other bachelors level (both are entry level, voluntary or academic lab exp, some level of lab needed. The Pre-Pivotal Drug Substance Technologies organization at Client develops, characterizes and supports clinical drug substance manufacturing processes for all early-stage programs in the Client portfolio. This lab-based position is located at our Thousand Oaks, CA site. The successful candidate will be responsible for support of the development, characterization, scale-up and support of upstream and downstream processes to enable clinical advancement of Client programs. This role is in an integrated bioprocess development group in which cell culture and purification scientists work together to advance Client rich, exciting and dynamic pipeline. With Client biology first approach, the position provides the unique opportunity to work on multiple modalities including antibodies, BiTEs, oncolytic viruses, bispecifics, and siRNAs. The successful candidate will design and execute experiments at the bench scale, spanning the end-to-end drug substance process, including both cell culture and purification operations. The candidate will apply established platform approaches and utilize problem-solving skills to rapidly solve day-to-day experimental challenges. Additionally, the candidate will utilize out-of-the-box thinking to contribute to technology development, including process automation. Finally, the candidate will also expand and develop skills in both cell culture and purification, thereby further contributing to the integrated group. Basic Qualifications: Bachelor’s or master’s degree OR Associate degree and 4 years scientific experience Preferred Qualifications: Master’s degree in Chemical Engineering, Biochemical Engineering, Life Sciences, or other relevant sciences with a demonstrated record of excellence. Basic understanding of protein chromatography and filtration processes and hands-on industry experience with purification operations. Prior experience with data analytical tools (Excel, Spotfire, etc.) is preferred. Experience with statistical analysis and programming in JMP, R, and/or Python environments is a plus. Team player with the ability to successfully work within a diverse team in a dynamic, cross-functional environment. Day to Day Responsibilities: • Work in a team environment to contribute to drug substance process development. • Complete mammalian cell culture experiments at different scales in shake flasks and bioreactors. • Implement purification experiments, mainly filtration and chromatography, at bench and pilot scale as needed. • Document experimental data in lab notebooks. • Analyze the data and present to the team. • Author technical reports and support regulatory filing as needed. • Contribute to technology development projects to seek continuous improvement in reliability and efficiency. • The candidate will have opportunities to work in cell culture development and purification development to become a well-rounded process development scientist with experience in upstream and downstream.