Analytical Scientist II

Job Title: Analytical Scientist II Job Description We are seeking a highly self-motivated, interactive, and productive hands-on scientist to join the Drug Discovery Sciences team. The successful candidate will have strong knowledge and extensive experience focused on liquid chromatography-mass spectrometry (LC-MS) analysis of small molecules and peptides in different biological matrices. You will work independently as well as collaboratively to generate high-quality data to drive programs forward. Responsibilities • Perform hands-on laboratory research and routine LC-MS/MS analysis of small molecules to support animal pharmacokinetic (PK), toxicokinetic (TK), PD and efficacy studies for drug discovery projects. • Conduct in vitro ADME experiments including in vitro stability and protein binding. • Acquire, process data, interpret results, and generate reports using software tools such as Sciex Analyst Software 1.7 and Sciex OS 2.0. • Generate PK reports using Phoenix 64 WinNonlin software in support of animal PK studies. • Collaborate with in vivo team to perform formulation and stability testing. • Prepare analytical protocols and results reports using MS Word, Excel, GraphPad, and PowerPoint. • Troubleshoot and maintain instruments to ensure analytical performance and data reliability. • Adapt new technology platforms and novel tools for DMPK challenges. • Maintain electronic laboratory notebook in accordance with intellectual property policies. • Adhere to safety practices and compliance with EH&S safety rules, and participate in mandatory training programs. Essential Skills • Strong knowledge in LC-MS analysis of small molecules and peptides. • Hands-on experience with LC-MS/MS, HRMS, and liquid handler for quantitation of small molecules in biological matrices. • Proficiency in using Phoenix 64 WinNonlin software for PK data analysis and report generation. • Ability to troubleshoot scientific equipment including LC-MS/MS. Additional Skills & Qualifications • Bachelor’s degree in related discipline with at least 2-5 years of related experience or Master’s degree with at least 1 year of related experience. • Experience with RapidFire/QTOF 6545XT and QTRAP 6500+ systems is a plus. Pay and Benefits The pay range for this position is $48.00 - $60.00/hr. Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits Available For This Temporary Role May Include The Following • Medical, dental & vision • Critical Illness, Accident, and Hospital • 401(k) Retirement Plan – Pre-tax and Roth post-tax contributions available • Life Insurance (Voluntary Life & AD&D for the employee and dependents) • Short and long-term disability • Health Spending Account (HSA) • Transportation benefits • Employee Assistance Program • Time Off/Leave (PTO, Vacation or Sick Leave) Workplace Type This is a fully onsite position in Alameda,CA. Application Deadline This position is anticipated to close on May 30, 2025. About Actalent Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 30,000 consultants and more than 4,500 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500. The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law. If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing due to a disability, please email actalentaccommodation@actalentservices.com for other accommodation options.