Analytical Scientist

Net2Source Inc. is an award-winning total workforce solutions company recognized by Staffing Industry Analysts for our accelerated growth of 300% in the last 3 years with over 5500+ employees globally, with over 30+ locations in the US and global operations in 32 countries. We believe in providing staffing solutions to address the current talent gap – Right Talent – Right Time – Right Place – Right Price and acting as a Career Coach to our consultants. Company: One of Our Clients Job Description: Job Title: Scientist I, Oligonucleotide Analytics Location: La Jolla, CA 92121 Duration: 12+ Months (Extendable) Pay Rate: $40.00 - 48.41/hr on W2 Top Three Skills: Operate LC-MS systems - Analyze and optimize methods - establish and automate high throughout analytical capabilities Key Responsibilities: 30% • Operating LC-MS systems to perform in-process and final QC of various scales of highly modified oligonucleotides, including siRNA and ASO, to support both discovery portfolio and pre-portfolio projects 20% • Optimize methods and improve analytical capabilities for novel Oligonucleotide synthesis 10% • Analyze and optimize methods in a project-specific way (i.e. GalNAc vs Cholesterol vs C16) by denaturing and non-denaturing HPLC methods. In addition, phosphoramidites or lipids by HPLC and LCMS. 20% • Establish and automate high throughput analytical capabilities and coordinate those efforts with higher synthesis throughput. 5% • Analyze oligonucleotides by HPLC-SEC, RP-IP and Ion-Exchange Chromatography. • Continue optimizing siRNAs using best-in class analytical chemistry methodologies such as different column matrixes for optimal siRNA characterization • Support integrity confirmation requests (such as concentration) by assay development and biology teams 3% • Conduct QC for lipid nanoparticle (LNP) formulations of mRNA 5% • Ensure the supply of laboratory consumables and reagents are in stock as needed • Maintain a high level of productivity in the laboratory setting. 2% • Present data and reports on project status at individual, group, and departmental meetings. Qualifications • Ph.D with 1-3 years of experience, performing progressively advanced duties at the Scientist level, or the equivalent training/experience is required. • Prior experience in the characterization of oligonucleotides and/or nucleoside/nucleotide analytes is required. Awards and Accolades: America's Most Honored Businesses (Top 10%) Awarded by USPAAC for the Fastest Growing Business in the US 12th Fastest Growing Staffing Company in USA by Staffing industry Analysts in the US (2020, 2019, 2020) Fastest 50 by NJ Biz (2020, 2019, 2020) INC 5000 Fastest growing for 8 consecutive years in a row (only 1.26% companies make it to this list) Top 100 by Dallas Business Journal (2020 and 2019) Proven Supplier of the Year by Workforce Logiq (2020 and 2019) 2019 Spirit of Alliance Award by Agile1 2018 Best of the Best Platinum Award by Agile1 2018 TechServe Alliance Excellence Awards Winner 2017 Best of the Best Gold Award by Agile1(Act1 Group)